Research conducted by Dr. Sina Rabbany, dean of the DeMatteis School of Engineering and Applied Science and a team of researchers at Weill Cornell Medicine and University of Texas Southwestern Medical School, was published this month in Nature Communications. The study, Molecular Determinants of Nephron Vascular Specialization in the Kidney, showed that the cells of blood vessels play a critical role in shaping the growth of other types of cells in the kidney. The study builds on an evolving view that the cells that line blood vessels, called endothelial cells, are the critical architects of tissue and organ development.
Kidney failure is a serious problem worldwide. While kidney transplantation is lifesaving, there aren’t enough kidneys available and recreation of kidneys through tissue engineering can help tackle an immense clinical need.