Dr. Sleiman Ghorayeb, Professor of Electrical Engineering in the Fred DeMatteis School of Engineering and Applied Science and Professor of Radiology and Molecular Medicine in the Hofstra Northwell School of Medicine, has collaborated on research with biomedical engineering alumna Zara Rahman (BE ’15) in the engineering school’s Ultrasound Research Lab. Their findings, which will be published in two journals in May 2017, could lead to advances in pediatric urology and early detection of fetal lung immaturity using ultrasound imaging.
Ms. Rahman conducted research with Dr. Ghorayeb under the Capstone senior design component, and she continued working with him after she graduated. She is currently enrolled in the postbaccalaureate premedical program at Columbia University.
For their first research project, Dr. Ghorayeb and Ms. Rahman collaborated with Drs. Patrick Samson, Christopher Hartman, Ricardo Palmerola, Michael Siev, and Lane S. Palmer of the Division of Pediatric Urology at Cohen Children’s Medical Center of New York. Their research led to a breakthrough in the field of pediatric urology. They developed a proprietary program at Hofstra that can be used as an objective parameter to determine the viability of a torsed testicle, which is when the cord that brings blood to the scrotum twists and reduces blood supply. The team chronicled their research and findings in a paper titled “Ultrasonographic Assessment of Testicular Viability Using Heterogeneity Levels in Torsed Testicles,” which will be published in the Journal of Urology, the most widely read and highly cited journal in the field.
The second article will be published in the Journal of Ultrasound in Medicine, a prominent journal in the field, and is based on collaborative research between Dr. Ghorayeb, Ms. Rahman, Drs. Luis A. Bracero and Matthew J. Blitz of the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Southside Hospital and North Shore University Hospital, and Dr. Martin L. Lesser, Director of the Biostatistics Unit, Feinstein Institute for Medical Research.
Using a novel technique implemented in a protocol that was developed in Hofstra’s Ultrasound Research Lab, the researchers aimed to differentiate preterm (less than 37 weeks gestation) and term (37-plus weeks gestation) fetal lungs. The study retrospectively evaluated women who had routine pregnancy ultrasound examinations at 20 weeks, which show standard fetal lung images. Their data suggests that decreased fetal lung maturity on ultrasound is associated with preterm fetuses.
“This is a great advance and revolution in the field of obgyn that will one day be used instead of current tests that assess fetal lung maturity such as amniocentesis,” Dr. Ghorayeb said.